|
|
5,10-methylenetetrahydromethanopterin + coenzyme_F420 + H+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced_coenzyme_F420
|
1.5.98.1
methylenetetrahydromethanopterin dehydrogenase
|
–
|
BMK
|
|
BRENDA:
BR1328
KEGG:
R04456
MetaCyc:
1.5.99.9-RXN
|
|
|
|
5-Methyl-5,6,7,8-tetrahydromethanopterin + coenzyme_F420 <=> 5,10-methylenetetrahydromethanopterin + reduced_coenzyme_F420
|
1.5.98.2
5,10-methylenetetrahydromethanopterin reductase
|
–
|
BMK
|
|
BRENDA:
BR29453
KEGG:
R04464
MetaCyc:
METHELENE-THMPT-OXI-RXN
SABIO-RK:
4147
|
|
|
|
5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 <=> 5,10-methylenetetrahydromethanopterin + H+
|
1.12.98.2
5,10-methenyltetrahydromethanopterin hydrogenase
1.12.99.6
hydrogenase (acceptor)
|
–
–
|
BMK
|
|
BRENDA:
BR37005
KEGG:
R04455
MetaCyc:
H2-METHYLENE-THMPT-DEHYDRO-RXN
|
|
|
|
5,10-methylenetetrahydromethanopterin + H2O <=> formaldehyde + 5,6,7,8-tetrahydromethanopterin
|
4.2.1.147
5,6,7,8-tetrahydromethanopterin hydro-lyase
|
–
|
BMK
|
|
BRENDA:
BR51000
KEGG:
R08058
MetaCyc:
RXN-2882
SABIO-RK:
12954
|
|
|
|
5,10-methylenetetrahydromethanopterin + NADP+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH
|
1.5.1
|
–
|
MK
|
|
KEGG:
R08059
MetaCyc:
RXN-2883
|
|
|
|
5,10-methylenetetrahydromethanopterin + glycine + H2O <=> 5,6,7,8-tetrahydromethanopterin + L-serine
|
2.1.2
2.1.2.1
glycine hydroxymethyltransferase
|
–
–
|
K
|
|
KEGG:
R09099
MetaCyc:
THMPT-SER-RXN
|
|
|
|
5,10-methylenetetrahydromethanopterin + 2-oxoisovalerate + H2O <=> ketopantoate + 5,6,7,8-tetrahydromethanopterin
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-15635
|
|
|
|
S-adenosyl-L-methionine + 5,10-methylenetetrahydromethanopterin + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + [4Fe-4S]+1_iron-sulfur_cluster + reduced_acceptor <=> 2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin + 5''-deoxyadenosine + L-methionine + 7,8-dihydromethanopterin + [4Fe-4S]2+ + acceptor
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-15732
|
|
|
|
5,10-methylenetetrahydromethanopterin + NAD+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH
|
1.5.1
|
–
|
|
|
MetaCyc:
RXN-2883_WOP
|
|
|
|
formaldehyde + 5,6,7,8-tetrahydromethanopterin <=> H2 + 5,10-methylenetetrahydromethanopterin
|
not assigned
|
–
|
|
|
SABIO-RK:
13044
|
|